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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK13
All Species:
24.85
Human Site:
S257
Identified Species:
49.7
UniProt:
O15264
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15264
NP_002745.1
365
42090
S257
L
N
D
K
A
A
K
S
Y
I
Q
S
L
P
Q
Chimpanzee
Pan troglodytes
Q9N272
365
41989
S257
L
N
D
X
A
A
K
S
Y
I
Q
S
L
P
Q
Rhesus Macaque
Macaca mulatta
XP_001112462
367
41940
N260
L
Q
S
D
E
A
K
N
Y
M
K
G
L
P
E
Dog
Lupus familis
XP_850384
366
42002
S257
L
N
D
K
A
A
K
S
Y
I
Q
A
L
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1B7
366
42053
S257
L
K
D
K
A
A
K
S
Y
I
Q
S
L
P
Q
Rat
Rattus norvegicus
Q9WTY9
366
42032
S257
L
K
D
K
A
A
K
S
Y
I
Q
S
L
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509537
374
42522
S257
L
Q
D
K
A
A
K
S
Y
I
Q
A
L
P
R
Chicken
Gallus gallus
P79996
382
43990
Y259
L
Q
P
T
V
R
N
Y
V
E
N
R
P
K
Y
Frog
Xenopus laevis
P47812
361
41700
N258
I
S
S
E
A
A
R
N
Y
I
Q
S
L
P
Y
Zebra Danio
Brachydanio rerio
Q9DGE2
361
41614
T258
M
P
S
H
E
A
R
T
Y
I
S
S
L
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61443
365
42080
N260
I
S
S
E
S
A
R
N
Y
I
R
S
L
P
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17446
377
43900
N268
I
S
S
E
E
A
R
N
Y
I
R
N
L
P
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
64.8
93.9
N.A.
92.9
91.8
N.A.
84.7
44.7
59.7
60
N.A.
56.4
N.A.
51.1
N.A.
Protein Similarity:
100
97.5
78.4
97.2
N.A.
97.2
96.1
N.A.
91.4
63.6
75.8
76.9
N.A.
73.1
N.A.
72.4
N.A.
P-Site Identity:
100
93.3
40
93.3
N.A.
93.3
93.3
N.A.
80
6.6
53.3
46.6
N.A.
40
N.A.
33.3
N.A.
P-Site Similarity:
100
93.3
66.6
100
N.A.
93.3
93.3
N.A.
93.3
6.6
86.6
66.6
N.A.
86.6
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
59
92
0
0
0
0
0
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
25
25
0
0
0
0
9
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
25
0
0
0
0
0
0
0
0
84
0
0
0
0
0
% I
% Lys:
0
17
0
42
0
0
59
0
0
0
9
0
0
9
9
% K
% Leu:
67
0
0
0
0
0
0
0
0
0
0
0
92
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
25
0
0
0
0
9
34
0
0
9
9
0
0
0
% N
% Pro:
0
9
9
0
0
0
0
0
0
0
0
0
9
92
0
% P
% Gln:
0
25
0
0
0
0
0
0
0
0
59
0
0
0
50
% Q
% Arg:
0
0
0
0
0
9
34
0
0
0
17
9
0
0
9
% R
% Ser:
0
25
42
0
9
0
0
50
0
0
9
59
0
0
0
% S
% Thr:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
92
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _